4-Bromo-N-(tert-butyl)-3-(trifluoromethyl)-benzensulfonamide is an organic compound whose main properties are as follows:
1. Appearance: 4-Bromo-N-(tert-butyl)-3-(trifluoromethyl)-benzenesulfonamide is white solid or crystalline powder.
2. Solubility: It has good solubility in general organic solvents, such as ethanol and dimethylformamide.
3. Melting point: Its melting point range is usually between 100-105°C.
4. Stability: It is stable at room temperature, but may decompose under high temperature or strong acid conditions.
4-Bromo-N-(tert-butyl)-3-(trifluoromethyl)-benzensulfonamide's main uses include:
1. Reagents in chemical synthesis.
2. As an intermediate in organic synthesis, used in the preparation of other compounds.
3. In drug research and development for the synthesis of drugs.
4-Bromo-N-(tert-butyl)-3-(trifluoromethyl)-benzenesulfonamide can be synthesized:
4-bromo-n-tert-butyl-3-aminobenzenesulfonamide and trifluoromethylphenylboronic acid undergo a condensation reaction to obtain the target product.
When using and handling 4-Bromo-N-(tert-butyl)-3-(trifluoromethyl)-benzenesulfonamide, you need to pay attention to the following safety information:
1. Avoid contact with skin and eyes. If contact with skin or eyes occurs, flush with plenty of water and seek medical help.
2. Appropriate personal protective equipment should be used during operation, such as laboratory gloves, eye protection glasses and laboratory coats.
3. Avoid inhaling dust or smoke. Good ventilation should be ensured during operation.
4. Do not contact the compound with strong oxidants or strong acids.
5. In storage should be away from high temperature, fire and flammable materials. Properly sealed and stored to avoid moisture.
When using and handling chemicals, always follow safe operating procedures and consult a professional if necessary.